BR0.3 0.3% Retinol + Bakuchiol - Babchi Renewing Serum

Designed as a biocompatible introduction to pure retinol, this is an intermediate strength retinoid suitable for beginners and users with sensitive skin, optimized by bakuchiol for enhanced stability and skin compatibility 0.3% pure retinol, stabilized and optimized for biocompatibility using 0.2% bakuchiol (a bioactive found in the babchi flower) Bakuchiol is a novel meroterpenoid (bioactive that serves as a natural secondary metabolite) found in the seeds and leaves of the babchi flower. Comparative gene expression profiling reveals that topical bakuchiol can operate as a functional analog of topical retinol in vitro, mimicking the biological functions and effects of retinol but through a secondary mechanistic pathway. Although bakuchiol is structurally different to retinol, it can bind to the same nuclear retinoic acid receptors (RARs) that regulate cell turnover. Due to this functional similarity, bakuchiol has been gaining popularity as a ‘natural’ alternative to retinol. But this use of bakuchiol as a retinol alternative doesn’t take advantage of their complementary mechanisms of action and bakuchiol’s complete phytochemical profile, especially as a broad spectrum antioxidant and anti-inflammatory agent that can help stabilize retinol against photooxidative and singlet oxygen breakdown as well as improve its skin tolerance.